产品货号：
Z11626
中文名称：
ASAH1抗体
英文名称：
Anti-ASAH1 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-ASAH1 Antibody |
| 指标别名 | AC;Acid ceramidase;Acylsphingosine deacylase;ASAH;ASAH1;HSD 33;PHP;PHP32;Putative 32kDa heart protein |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB,IHC,ICC/IF,ELISA |
| 基因名称 | ASAH1 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | E.coli-derived human ASAH1 recombinant protein (Position:H63-I393). |
| 实际分子量 | 45KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | The ASAH1 gene encodes in humans the acid ceramidase enzyme.It is mapped to 8p22.This gene encodes a member of the acid ceramidase family of proteins.Alternative splicing results in multiple transcript variants,at least one of which encodes a preproprotein that is proteolytically processed.Processing of this preproprotein generates alpha and beta subunits that heterodimerize to form the mature lysosomal enzyme,which catalyzes the degradation of ceramide into sphingosine and free fatty acid.This enzyme is overexpressed in multiple human cancers and may play a role in cancer progression.Mutations in this gene are associated with the lysosomal storage disorder,Farber lipogranulomatosis,and a neuromuscular disorder,spinal muscular atrophy with progressive myoclonic epilepsy. |
| Uniprot ID | Q13510 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 基因名全称 | N-acylsphingosine amidohydrolase 1 |
| 蛋白名全称 | Acid ceramidase |
| 推荐稀释比 | Western blot(WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:50～400 Immunocytochemistry in fixed cells 1:50～400 (ELISA)： 1:100～1000 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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